WBC world heavyweight champion Deontay Wilder will defend his title against Luis Ortiz on Saturday, 3 March at the Barclays Center in New York.
November’s original fight was postponed after Ortiz failed a drug test.
Ortiz was fined $25,000 (£18,497) but not banned from the sport as the World Boxing Council said the Cuban took the drugs for high blood pressure.
American Wilder has won all 39 of his professional fights, all but one inside the distance. Ortiz has won all 28.
Britain’s Anthony Joshua, who holds the IBF and WBA world heavyweight belts, is in talks with WBO champion Joseph Parker of New Zealand over a potential fight at Cardiff’s Principality Stadium on 31 March.
No boxer has held the WBC, IBF, WBA and WBO world heavyweight belts.